Mirtazapine side effect sexual

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It can occur secondary to physical or mental disorders, substance abuse and treatment with prescription drugs like antidepressants. We wanted to study the prevalence of sexual dysfunction associated with antidepressant use in the psychiatric unit of a tertiary care hospital and assess for causality, severity and preventability. We did a retrospective data collection from case records of patients on antidepressants from the Psychiatry outpatient clinic of a tertiary care teaching hospital during the period 1 st January to 31 st Decemberexcluding those with complaints of sexual dysfunction prior to treatment.

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She then began taking antidepressant medication. Her libido nosedived. She began struggling to orgasm, and sex with her husband of 10 years dwindled to one encounter every few months.

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Resulting sexual dysfunction can impair quality of life and intimate relationships and discourage patients from taking antidepressants Box 12. Although most reports have focused on SSRIs, all antidepressant classes have been associated with sexual dysfunction, with prevalence likely influenced by differences in neurotransmitter modulation Table 2. A recent study reported similarly high rates with mirtazapine, but its small sample size limits conclusions about side effect prevalence with this drug.

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Sexual side effects are common with antidepressants in both men and women, so your concern is understandable. Effects on sexual function can include:. The severity of sexual side effects depends on the individual and the specific type and dose of antidepressant.

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Mirtazapine is a newer antidepressant that exhibits both noradrenergic and serotonergic activity. It is at least as effective as the older antidepressants for treating mild to severe depression. Sedation is the most common side effect. Although agranulocytosis is the most serious side effect, it is rare approximately one in 1, and usually reversible when the medication is stopped.

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